CERTAIN bacteria possess the ability to assimilate (glutaimc acid and to concentrate this amino-acid in the free state within the internal environment1. Glutamic acid cannot pass through the bacterial cell-wall by free diffusion as the migration requires energy whigh can be supplied by exergonic metabolism such as the fermentation of glucose by the organism. At equilibrium the concentration of glutamic acid in the internal environment is markedly greater than that在外部环境中保持。由于对大量细菌物种的调查表明，这种吸收和浓缩谷物酸的能力仅限于革兰氏阳性生物2，因此决定调查对各种化学治疗剂的同化过程的作用 ，这些过程已知可以区分革兰氏阳性和革兰氏阴性细菌。
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